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PlotThe frontier is the red band.
The frontier is defined as containing those trials for which there are no trials both more recent and published in a journal with a AI Score higher than the specified width of the frontier.
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Citations found
Total: 12
Frontier
Hypothesis: These studies are considered in the Frontier and should be reviewed by a clinician needing to make a decision.
- Treatment of hypertension in patients 80 years of age or older. N Engl J Med. 2008. PMID: 18378519 AI Score: 21.64
- Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet. 1997. PMID: 9297994 AI Score: 14.57
- Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet. 1991. PMID: 1682683 AI Score: 14.57
- Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group. JAMA. 1991. PMID: 2046107 AI Score: 13.11
- Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial. Lancet. 1985. PMID: 2861311 AI Score: 14.57
- Hypotensive therapy in stroke survivors. Lancet. 1970. PMID: 4190177 AI Score: 14.57
Citations not on frontier
Hypothesis: These citations are considered outside of the frontier and could safely be ignored by a clinician needing to make a decision.
- Results of the pilot study for the Hypertension in the Very Elderly Trial. J Hypertens. 2003. PMID: 14654762 AI Score: 1.245
- Medical Research Council trial of treatment of hypertension in older adults: principal results. MRC Working Party. BMJ. 1992. PMID: 1445513 AI Score: 6.287
- Morbidity and mortality in the Systolic Hypertension in the Elderly Program (SHEP) pilot study. Stroke. 1989. PMID: 2911834 AI Score: 2.264
- Randomised trial of treatment of hypertension in elderly patients in primary care. Br Med J (Clin Res Ed). 1986. PMID: 3094811 AI Score: 6.287
- Blood pressure reduction in elderly: a randomised controlled trial of methyldopa. Br Med J (Clin Res Ed). 1981. PMID: 6794796 AI Score: 6.287
Additional citations below the limits of the plot.
No citations
Article influence score not available
- Prospective study on the treatment of mild hypertension in the aged. Jpn Heart J. 1981 ISSN: 0021-4868 ISSNlinking: 0021-4868. PMID: 7012398
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